Fast Eddie + hot mike = major faux pas.

Gov. Rendell is in hot water over remarks he made Tuesday about Arizona Gov. Janet Napolitano, President-elect Barack Obama's selection to lead the Department of Homeland Security.

Caught on a microphone at the National Governors Association meeting here, Rendell said Napolitano was perfect for the job because she "has no family" and "no life."

Napolitano, a second-term governor, has no children and has never been married.

CNN anchor Campbell Brown caught the comment and slammed Rendell Tuesday night on her show, "No Bias, No Bull."

"If a man had been Obama's choice for the job, would having a family or not having a family ever even have been an issue? Would it have ever prompted a comment? Probably not," Brown said.

The entire comment from Rendell was: "Janet's perfect for that job. Because, for that job, you have to have no life. Janet has no family, perfect. She can devote, literally, 19 to 20 hours a day to it."

Rendell's spokesman Chuck Ardo said Rendell had meant no offense.

"The governor was discussing the requirements of the office," Ardo said. "He believes anyone who reaches that level of government, be that person male or female, can't have much of a life outside the office. And he uses himself as an example and can often be heard saying he has no life."

Napolitano's press office did not return a call for comment. *