EAST RUTHERFORD, N.J. - New York Giants leading rusher Derrick Ward broke his leg Sunday against the Chicago Bears and will be out indefinitely.

Ward fractured his left fibula, the thinner of the two bones extending from the knee to the ankle, in the fourth quarter of New York's 21-16 come-from-behind victory. He rushed 24 times for a career-high 154 yards.

The fourth-year player leads the Giants with 602 yards despite missing the previous four games due to ankle and groin injuries.

"It's tough to deal with," Ward said. "I'll bounce back from this like I bounced back from all the other ones."

Brandon Jacobs, the opening day starter who has missed the last two games with a hamstring injury, could replace Ward on Sunday at Philadelphia.