Curt Schilling won't run for Edward M. Kennedy's seat in the U.S. Senate.

The former Boston Red Sox pitcher made the announcement on "Joe Buck Live" on HBO last night. Earlier this month, the 42-year-old Schilling expressed interest in running for the seat held by the Massachusetts Democrat for almost 50 years before he died in August.

Kennedy was first elected to the Senate in 1962. He died Aug. 25 of brain cancer at age 77. Primaries are scheduled for Dec. 8, and the general election will be Jan. 19.

Schilling won titles with the Arizona Diamondbacks in 2001 and again with the Red Sox in '07. He also pitched for the Phillies, helping them reach the 1993 World Series. He retired in March.

Gov. Deval Patrick could announce a temporary replacement for Kennedy as soon as tomorrow.

Noteworthy

* Roger Clemens, who last pitched for the New York Yankees in 2007, filed an appeal of his dismissed defamation suit against Brian McNamee.

Clemens filed a notice Friday with the 5th U.S. Circuit Court of Appeals to review the decisions of U.S. District Judge Keith P. Ellison, who threw out most of Clemens' case in February and dismissed the remainder of the suit Aug. 28.

The seven-time Cy Young Award winner sued his former personal trainer in Texas state court in January 2008, a month after McNamee's accusations against the pitcher were published in the Mitchell Report. The suit was moved a month later to federal court in Houston.

McNamee claimed in the Mitchell Report that he injected Clemens with steroids and human growth hormone at least 16 times in 1998, 2000 and 2001. He also sued Clemens for defamation on July 31 in federal court in Brooklyn, N.Y.

* Supreme Court Justice Sonia Sotomayor is coming off the bench - and heading to the mound at Yankee Stadium.

Sotomayor, a Yankees fan from the Bronx, is scheduled to throw out the ceremonial first pitch Saturday before New York's game against Boston.

In games last night:

* At Cleveland, Edwin Jackson (13-7) pitched seven shutout innings and remained unbeaten against Cleveland as the first-place Tigers defeated the Indians, 3-1.

* At St. Petersburg, Fla., Jose Lopez hit a tiebreaking home run in the eighth inning and the Seattle Mariners beat the Tampa Bay Rays, 4-3, eliminating the defending AL champions from the postseason.

* At Toronto, Aaron Hill doubled in the game-winning run in the 11th inning to lead the Blue Jays to a 6-5 win over the Baltimore Orioles.

Hill, who hit a solo home run in the third, reached 100 RBI for the first time in his 5-year career.

* At Chicago, Michael Cuddyer hit a go-ahead home run in the sixth and Matt Tolbert homered in the same inning and the Minnesota Twins defeated the Chicago White Sox, 8-6.

* At Kansas City, Zack Greinke (15-8) held Boston to two hits in six scoreless innings to lead the Royals to a 5-1 victory over Paul Byrd (1-2) and the Red Sox.

* At Oakland, The New York Yankees clinched a playoff spot when the Athletics defeated the Texas Rangers, 9-1.