Orlando City at Houston Dynamo

7 p.m. Friday

(UniMás, Univision Deportes)

After getting a raucous reception from more than 62,000 fans at the Citrus Bowl last weekend, Major League Soccer expansion club Orlando hits the road for the first time. Kaká is the big name for the Lions, while Amobi Okugo is well known to Union fans. But the rising star may be 20-year-old Honduran forward Bryan Rochez, who has a ferocious shot. Houston's strength is in its midfield, with veterans Brad Davis, Óscar Boniek García, Giles Barnes, and Ricardo Clark.

Southampton at Chelsea

9:30 a.m. Sunday

(NBC-SN, NBC Universo)

Chelsea was knocked out of the Champions League in stunning fashion on Wednesday, giving up a late goal to Paris Saint-Germain despite having a man advantage from the 31st minute. Returning to the English Premier League, the first-place Blues may have to call on some of their bench players, but when the reserves include Colombian World Cup star Juan Cuadrado and French star Loïc Remy, it's not a worry. Southampton has slipped in recent weeks. It appears Graziano Pellè and the Saints will have difficulty gaining a qualifying spot for the European tournaments.

New England Revolution at New York City FC

5 p.m. Sunday

(ESPN2, ESPN Deportes)

MLS officially arrives in New York for the first time as NYC FC, jointly run by Major League Baseball's Yankees and the EPL's Manchester City, takes the field at Yankee Stadium. It will be a big test for David Villa and Mix Diskerud. Diego Fagundez, Juan Agudelo, and the Revs arrive in the Bronx in a bad mood after being routed in Seattle.

Los Angeles Galaxy at Portland Timbers

7 p.m. Sunday

(Fox Sports 1, Fox Deportes)

Portland midfielder Diego Valeri is one of MLS's elite playmakers. L.A. counters with reigning MVP Robbie Keane, who scored a fine volley in last weekend's decisive win over Chicago.

Arsenal at Monaco

3:45 p.m. Tuesday

(Fox Sports 1, ESPN Deportes)

Monaco's 3-1 win at Arsenal in the first leg of their Champions League round of 16 series was one of the most stunning results in the tournament's history. Now Santi Cazorla, Danny Welbeck, and the Gunners must win on the road by at least three goals in order to advance. Les Rouges et Blancs have a stingy defense led by Portuguese veteran Ricardo Carvalho, and a deceptive attack reliant on Bulgarian striker Dimitar Berbatov.

Manchester City at Barcelona

3:45 p.m. Wednesday

(Fox Sports 1, ESPN Deportes)

Lionel Messi and Barcelona have won 15 of 17 games in all competitions since the beginning of the year. That includes a 2-1 victory in Manchester in the first leg of this Champions League round of 16 series. Sergio Agüero and City will head south believing they have a chance, but do they have the horsepower to win the high-scoring game they need to advance?

- Jonathan Tannenwald