Colts (13-0) at Jaguars (7-6)

8:20 p.m., Jacksonville Municipal Stadium. (NFL Network)

Line: Colts by 3

It's the last home game for the Jaguars, and they need a big-time upset to stay in the playoff race. Sunday's loss to a fellow contender, Miami, was a step in the wrong direction.

There reportedly will be a large crowd watching a Jaguars game for the first time all season, but Peyton Manning is poised and the Colts appear invincible, having won 22 regular-season games in a row.

- Matt Gelb