Six people were injured when a car jumped a curb and struck three pedestrians and then crashed into another car Friday afternoon in Center City, police said.

The pedestrians — three women ages 64, 51, and 39 — were listed in critical condition at Thomas Jefferson University Hospital, police said. The oldest woman was reported in very critical condition.

A Jefferson spokesperson said the hospital received six people from the accident, with three in critical and the remaining in fair condition as of 8:15 p.m.

The accident occurred about 4:05 p.m. at 10th and Chestnut Streets, about a block from the hospital’s emergency room. The Dodge, which was being operated by a 68-year-old man, was heading south on 10th when it hit the pedestrians and then hit a blue Nissan Rogue.

Two men ages 31 and 56, and a woman, 57, in the Nissan were taken to Jefferson and were listed in stable condition, police said.

The driver of the Dodge, a 68-year-old man, remained at the scene.

The cause of the accident was under investigation.