BALTIMORE – Eagles offensive lineman Allen Barbre is inactive Sunday against the Baltimore Ravens because of a hamstring injury, meaning rookie Isaac Seumalo will start at right tackle and the Eagles have their sixth starting offensive-line combination this season.

Right guard Brandon Brooks is back in the lineup after missing two of the past three games because of an illness related to anxiety. Wide receivers Jordan Matthews (ankle) and Dorial Green-Beckham (abdomen) are also active, even though they were listed as questionable.

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The other inactives are wide receiver Paul Turner, cornerback Dwayne Gratz, running back Darren Sproles, defensive end Steven Means, tackle Halapoulivaati Vaitai, and defensive tackle Taylor Hart.

Seumalo, who has started two games at right guard this season, is an interior lineman who is playing tackle only because the three other backup options to suspended Lane Johnson are injured. The starting line will be Jason Peters at left tackle, Stefen Wisniewski at left guard, Jason Kelce at center, Brooks at right guard, and Seumalo at right tackle. Josh Andrews and Dillon Gordon are the backups. It's the first game Gordon is playing this season.

Sproles is inactive because of a concussion. Ryan Mathews and Kenjon Barner will be the top two running backs, with rookie Byron Marshall making his debut as the No. 3 running back.

Turner is inactive because the Eagles are playing only four wide receivers and Matthews and Green-Beckham are both in the lineup. Nelson Agholor and Bryce Treggs are the other wide receivers.

Means was active last week, but the Eagles went back to five defensive ends. Linebacker Kamu Grugier-Hill is active after sitting last week.