The University of Pennsylvania Health System is preparing to begin work on its New Patient Pavilion, an oblong structure of glass and tan aluminum that will occupy the former site of the university's Penn Tower building.

Design and construction of the new building, by a team involving architects Foster & Partners, is to begin before the end of the fall, according to a project description posted Wednesday to the website of Philadelphia's Civic Design Review board.

The panel, which offers nonbinding design suggestions for the city's biggest development projects, is scheduled to review the project on Nov. 29.

The 15-story, 1.25 million-square-foot New Patient Pavilion at South 33rd Street and Convention Avenue will include 500 inpatient rooms, 47 operating rooms, and an emergency section, as well as a 665-space underground parking garage, according to the description.

Also planned are elevated walkways to link the new building with the nearby Hospital of the University of Pennsylvania and the Perelman Center for Advanced Medicine.