Arlen Specter dead at 82

Legendary Pennsylvania Senator Arlen Specter died in his home Sunday morning from complications of non-Hodgkins Lymphoma, according to a statement released by his family. He was 82.

Specter, 82, announced in 2005 that he had Hodgkin's disease, for which he underwent chemotherapy. He was treated again in 2008, after the disease returned. He was again hospitalized in August to deal with the disease.

Specter's funeral will be open to the public and held at Har Zion Temple in Penn Valley. Internment will immediately follow at Shalom Memorial Park in Huntingdon Valley.

The family asks that contributions be made in lieu of flowers to Philadelphia University or another charity.

Specter rose to prominence in the 1960s as an aggressive Philadelphia district attorney and as an assistant counsel to the Warren Commission, developing the single-bullet theory that posited just one bullet struck both President Kennedy and Texas Gov. John Connally — an assumption critical to the argument that presidential assassin Lee Harvey Oswald acted alone. The theory remains controversial and was the focus of Oliver Stone's 1991 movie "JFK."

In 1987, Specter helped thwart the Supreme Court nomination of former federal appeals Judge Robert H. Bork — earning him conservative enemies who still bitterly refer to such rejections as being "borked."

But four years later, Specter was criticized by liberals for his tough questioning of Anita Hill at Clarence Thomas' Supreme Court nomination hearings and for accusing her of committing "flat-out perjury." The nationally televised interrogation incensed women's groups and nearly cost him his seat in 1992.

Specter, who had battled cancer, was Pennsylvania's longest-serving senator when Democrats picked then-U.S. Rep. Joe Sestak over him in the 2010 primary, despite Specter's endorsements by President Barack Obama and other Democratic leaders. Sestak lost Specter's seat to conservative Republican Rep. Pat Toomey by 2 percentage points.

A political moderate, Specter was swept into the Senate in the Reagan landslide of 1980.

He took credit for helping to defeat President Clinton's national health care plan — the complexities of which he highlighted in a gigantic chart that hung on his office wall for years afterward — and helped lead the investigation into Gulf War syndrome. Following the Iran-Contra scandal, he pushed legislation that created the inspectors general of the CIA.

As a senior member of the powerful Appropriations Committee, Specter pushed for increased funding for stem-cell research, breast cancer and Alzheimer's disease, and supported several labor-backed initiatives in a GOP-led Congress. He also doggedly sought federal funds for local projects in his home state.

The former Democrat was not shy about bucking fellow Republicans.

In 1995, he launched a presidential bid, denouncing religious conservatives as the "fringe" that plays too large a role in setting the party's agenda. Specter, who was Jewish, bowed out before the first primary because of lackluster fundraising.

Despite his tireless campaigning, Specter's irascible independence caught up with him in 2004. Specter barely survived a GOP primary challenge by Toomey by 17,000 votes of more than 1.4 million cast. He went on to easily win the general election with the help of organized labor, a traditionally Democratic constituency.

Specter startled fellow senators in April 2009 when he announced he was switching to the Democratic side, saying he found himself "increasingly at odds with the Republican philosophy." Earlier in the year, he had been one of only three Republicans in Congress — and the only one facing re-election in 2010 — who voted for

President Barack Obama's economic stimulus bill.

He also said he had concluded that his chance of defeating a GOP challenger in the 2010 party primary was bleak. But he said the Democrats couldn't count on him to be "an automatic 60th vote" to give the party a filibuster-proof majority.

-- The Associated Press contributed to this report.