Ohio State at Michigan State, noon, ESPN:
This isn't the same Spartans team that last year knocked the Buckeyes out of the Big Ten and national championship races and took its own seat at the College Football Playoff table. And with Ohio State having put up 62 points the last two weeks, it could be ugly.
Florida at LSU, 1 p.m., SEC Network: This game was rescheduled because of Hurricane Matthew but was moved from Gainesville to Baton Rouge. That hurts the Gators, who are one win away from clinching the SEC East, and helps the Tigers, who are making a late bid to get into a New Year's Six bowl.
Indiana at Michigan, 3:30 p.m., ESPN: Back in the friendly confines of the Big House, the Wolverines try to recover from the shock of last week's upset loss at Iowa. The Hoosiers showed a week ago that they could move the ball effectively on Penn State but five turnovers thwarted their upset bid.
Oklahoma at West Virginia, 8 p.m., 6ABC: The winner gets a leg up on the Big 12 race while hoping to favorably influence the College Football Playoff committee. The Sooners, who have rocketed into ninth place in the CFP rankings, clinch the conference crown with a win and an Oklahoma State loss.