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Thanksgiving NFL game odds, spreads and picks | Vegas Vic

The Redskins are hosting a Thanksgiving game for the first time in their history. Look for them to feast on the Giants.

The Cowboys, shown here watching Corey Clement score a touchdown on Sunday, are a slight home underdog to the Chargers.
The Cowboys, shown here watching Corey Clement score a touchdown on Sunday, are a slight home underdog to the Chargers.Read moreClem Murray / Staff

Vikings (-3) at LIONS (O/U: 44.5), 12:30 p.m. (Fox)

Quick hit: Five of the Lions last six games have gone over … Detroit has won four in a row on Thanksgiving.

Vikings vs. spread: 7-3

Lions vs. spread: 5-4-1

Vegas Vic's take: Sure Detroit rolls in with a three game winning streak, but the Ws have come against the Packers WITHOUT Aaron Rodgers, the Browns, WITHOUT a clue, and the 3-7 Bears. NOT impressed.

Chargers (-1) at COWBOYS (O/U: 48), 4:30 p.m. (CBS)

Quick hit: Dak Prescott had 16 touchdown passes, four interceptions and a 97.9 passer rating in the first eight games for Dallas. In the last two, he has zero TD passes, three picks and a Cleveland Browns-esque 55.4 rating.

Chargers vs. spread: 5-4-1

Cowboys vs. spread: 5-5

Vegas Vic's take: Lean to the Chargers -1 point over the Cowboys. Dallas without Ezekiel Elliott is a wounded duck, but not thrilled with the Lightning Bolts as a road favorite.

Giants at REDSKINS (-7) (O/U: 44.5), 8:30 p.m.

Quick hit: The only team that has given up more points than the Redskins' defense (26.6 per) is the Colts (28.0).

Giants vs. spread: 4-6

Redskins vs. spread: 4-6

Vegas Vic's take: No problem for the D.C. kids on the offensive side, scoring 61 points the last two times out. It's the D that has been suspect. But with the New Yorkers coming to town, averaging only 14 points per game the last month, it should be a sweet evening for the home side.