The already wounded 76ers had to play most of Saturday night's game without their floor general.

Ben Simmons left the game with back tightness in the first quarter of a 116-115 victory over the Orlando Magic at Wells Fargo Center.

JJ Redick drained a three-pointer with 17 seconds left to put the Sixers ahead by two (116-114). The Magic pulled within one on Aaron Gordon's foul shot with eight seconds left.  Orlando had a chance to win the game in the closing seconds. But Terrance Ross misfired on a three-pointer with two seconds left. Joel Embiid came up with the defensive rebound before the buzzer sounded.

The victory improved the Sixers to 2-1 heading into Tuesday night's game against the Detroit Pistons at Little Caesars Arena. It was their second straight victory after suffering an 18-point season-opening loss to the Boston Celtics at TD Garden.

Embiid finished with 32 points, while Redick added 31.

But a lot of the attention was on Simmons leaving the game.

He received treatment during the game. His status moving forward was not known while the game was in progress.

Simmons left the game with 4 minutes, 19 seconds left in the first quarter. He hobbled to the locker room after being subbed out. After being evaluated, the 2017-18 rookie of the year was ruled out the rest of the game. It appeared that Simmons might have injured himself shortly after the game started, but remained in the contest.

The Sixers are already without their top three offseason acquisitions — Wilson Chandler (strained left hamstring), Mike Muscala (sprained right ankle), and Zhaire Smith (broken left foot) — along with reserve guard Jerryd Bayless (sprained left knee).

There's a chance Muscala could return this week. Chandler hopes to return this upcoming Saturday against the Charlotte Hornets. Bayless could return in around three weeks.

But Embiid had another dominating performance for the shorthanded squad.

He made 13 of 26 shots – including making 3 of 5 three-pointers – to go with 10 rebounds and three assists.

Embiid did most of his damage in the first half. That's when the All-Star center finished with 21 points on 8-for-14 shooting.  He made 3 of 4 three-pointers. Embiid has now recorded the last two 20-point halves by a Sixer. His last one came on Feb.9.

Redick added 31 points while making 8 of 13 three-pointers in a reserve shooting guard role. Markelle Fultz had eight points, seven assists, and four rebounds. The starting shorting guard assumed the primary ball handling duties once Simmons left the game.

As a result, he remained in the starting lineup at the start of the second half.  Redick had replaced him in the starting lineup after intermission in the first two games. But they both started due to Simmons' injury.

The Magic jumped out to an early 9-0 advantage 2 minutes, 5 seconds into the game, forcing the Sixers to call timeout.  At the time, Orlando shot 4-for-5, while the Sixers were 0-for-3 from the field.

Dario Saric hit a three following the timeout, Evan Fournier answered with his second three-pointer.  The Magic opened up a 17-4 advantage after Jonathan Isaac's three-pointer.

The Sxers made their second basket in 11 attempts on Fultz's dunk to pull the Sixers within 11 points (17-6). But Orlando went onto lead by as many at 16 points in the opening quarter.

The Sixers pulled within two points (32-30) on Redick's three-pointer at the conclusion of the first quarter.

They took their first lead 33-30 on Redick's three-pointer 35 seconds into the second quarter. The Sixers went on to lead by as many as 13 points late n the second quarter.

The Magic took a two-point lead (112-110) on Terrence Ross 42-foot shot-clock beat  three-pointer with 1:24 left.

Redick hit a three-pointer on an Embiid assist to put the Sixers up 116-114 with 17 seconds left.

This game was sort a homecoming for former Westtown School and Texas standout Mo Bamba (five points, three blocks.)

"I used to come here and watch games," the 20-year-old said of Wells Fargo Center. "It feels like everything kind of happened not too long ago."

The Harlem native spent his sophomore, junior and senior years of high school at Westtown.  He was regarded as nation's second-best college prospect in the Class of 2017 by recruiting services Scout.com and Rivals.com.

Bamba was the Big 12 newcomer of the year in his lone season at Texas. The Magic selected him with the sixth-overall pick in June's NBA draft.

"I know there's going to be a bunch of Westtown students up there," he said of the stands before the game. "This city really feels like a second, second home."

Bamba and has close relationship with Embiid. The two worked out this summer with shooting coach Drew Hanlen in a group that included Fultz. Embiid serves as mentor who gives him pointers on his game.'

There's a chance Muscala could return this week. Chandler hopes to return this upcoming Saturday against the Charlotte Hornets. Bayless could return in around three weeks.