Beginning Sunday, March 22, fermented grapes get the spotlight during Philly Wine Week. Through Sunday, March 29, restaurants throughout Philadelphia honor this second annual festival with events to fill your glass.

Here are some noteworthy events.

Sunday, March 22

Pop your cork for the start of Philly Wine Week during Opening Corks at the Pennsylvania Academy of the Fine Arts (118 N. Broad St.). Beginning at 5 p.m., the gala features sparkling wines as well as white and rosé. Hors d'oeuvres will be served throughout the evening. Tickets are $75 and cocktail attire is required.

Monday, March 23

Starting at 4 p.m., (135 S 18th St.) hosts a tasting of Sancerre with winemaker Sébastien Riffault and importer Zev Rovine. For $35, guests will taste three hand-picked selections while learning about the creation of the wines.

Watch as some of the city's finest bartenders square off at Panorama (Penn's View Hotel, 14 N. Front St.) during a wine-cocktail competition called Bar-Somm. Smack Down. For $18, you'll get to try each of the cocktails and vote for your favorite. The competition starts at 7:30 p.m.

Tuesday, March 24

Perfect for the couple split between their love of grapes and hops, World Café Live (3025 Walnut St.) presents He Said "PA Beer," She Said "PA Wine."  Starting at 6:30 p.m., the Pennsylvania Winery and Victory Brewing will present pairings to win over the guests on a People's Choice Award. The dinner costs $55 per person and doors open at 6:30 p.m.

Khyber Pass Pub's Johnny Medlinsky and his beer selections square off against David McDuff's portfolio of Bowler Wines at Alla Spina (1410 Mt. Vernon St.) during a boozy Cage Match. The event starts at 6:30 p.m. and the rules are pretty simple: Taste the pairings and vote for your favorite. Dinner is priced at $65.

Wednesday, March 25

Learn the art of wine and cheese pairings at Jet Wine Bar (1525 South St.) during Peril and Pleasure. From 6:30 to 8 p.m., get the inside scoop on what goes and what doesn't when enjoying cheese with wine. Tickets are $20 per person.

Whether you're into international or national wines, Paradiso's (1627 E. Passyunk Ave.) Old World vs. New World event will satisfy your taste buds. For $25 you'll get to taste two Chardonnays, and two Pinot Noirs, with one each being from Italy and California. The event starts at 6:30 p.m.

Thursday, March 26

Take part in a Murder Mystery dinner at London Grill (2301 Fairmount Ave.), where guests will play along to help discover who killed the Paris Night Club owner moments before dining. The comic show starts at 6:30 p.m. and includes dinner and wine pairings. Tickets are $70 in advance and $80 at the door.

Friday, March 27

Get creative with your wine glass at Bistro St. Tropez (2400 Market St.) during Drinkable Acts. From 6 to 8 p.m., paint your own glass with the provided supplies and enjoy food and drink selections from chef Patrice Rames. Tickets are $30 per person.

At 6 to 9 p.m., Pinot Boutique (227 Market St.) hosts winemakers from Paradocx Vineyard for an evening of tastes and talks. After you're done chatting, featured wines during the event will be available to purchase.

Saturday, March 28

Create your very own Meritage, a blend of wines, at Vintage Wine Bar and Bistro (129 S. 13th St.) from 2 to 4 p.m. Tickets are $45 per person and includes light food fare, wine from Lyeth Estates, and prizes for the best blends.

Sunday, March 29

Take your last gulp of Philly Wine Week at Tria Rittenhouse (123 S. 18th St.) or Tria Washington West (1137 Spruce St.) during a special Sunday School Class all about López de Heredia Rioja Blanco 2005. The class starts at noon and will give visitors exclusive tastes and lessons about aged wine.

For more Things to Do, check out our calendar for the most up-to-date happenings.