Insider Transactions

Securities trades recently reported to the Securities and Exchange Commission by officers, directors and principal shareholders of corporations based or having sizable employment in the Philadelphia area. Titles are as reported to the SEC.

Ted I. Kaminer

, chief financial officer, sold 4,000 shares at $8.80 to $8.97 on Dec. 19, and now directly holds 116,600 shares.

John P. Neafsey

, director, bought 2,132 shares at $3.44 to $3.50 on Dec. 24, and now directly holds 34,167 shares.

Angus F. Smith

, director, bought 1,342 shares at $3.40 to $3.48 on Dec. 21, and now directly holds 19,728 shares.

Jack Farber

, board chairman, sold 55,931 shares at $39.60 to $40.20 on Dec.19 to Dec. 21, and now indirectly holds 799,530 shares.

Jeffrey A. Weiss

, chief executive officer, sold 17,000 shares at $26.81 to $28.00 on Dec. 17 to Dec. 18, and now directly holds 435,300 shares.

R. Frank Ecock

, director, bought 20,000 shares at $1.72 to $1.75 on Dec. 20, and now directly holds 38,333 shares.

Xmark Opportunity Partners L.L C

., beneficial owner, bought 247,991 shares at $1.74 to $2.42 on Dec. 20 to Dec. 21, and now indirectly holds 3,935,130 shares.

Frank Gerardi

, beneficial owner, bought 9,871 shares at $1.05 to $1.06 on Dec. 17 to Dec. 19, and now indirectly holds 1,662,770 shares.

14159 Capital GP L.L.C.

, beneficial owner, bought 4,544 shares at $10.58 to $10.61 on Dec. 18 to Dec. 19, and now indirectly holds 94,961 shares.

Baker Biotech Capital GP L.L.C.

, director and beneficial owner, bought 56,495 shares at $10.58 to $10.61 on Dec. 18 to Dec. 19, and now indirectly holds 2,592,220 shares.

Baker Bros. Capital GP L.L.C.

, director and beneficial owner, bought 390 shares at $10.58 to $10.61 on Dec. 18 to Dec. 19, and now indirectly holds 278,903 shares.

Baker Bros. Life Sciences Capital GP L.L.C.

, director and beneficial owner, bought 143,022 shares at $10.58 to $10.61 on Dec. 18 to Dec. 19, and now indirectly holds 4,276,690 shares.

Harold N. Chefitz

, director, sold 1,690 shares at $30.34 to $30.45 on Dec. 19, and now directly holds 8,916 shares.

James O. Ellis

Jr.

, director, bought 200 shares at $108.33 to $108.34 on Dec. 19, and now directly holds 200 shares.

Mark E. Pasquerilla

, director, sold 50,000 shares at $29.30 to $29.50 on Dec. 19, and now indirectly holds 1,103,230 shares.

Harris Wildstein

, director, bought 1,000 shares at $7 on Dec. 18 to Dec. 21, and now directly holds 618,581 shares.

SOURCES: Thomson Financial; Securities and Exchange Commission filings