Tired Hands Brewing Co. is coming to Philadelphia. Again.

The Ardmore brewery announced on Instagram Monday that it will soon bring its first brick-and-mortar outpost to town in the form of St. Oner’s, a restaurant planned for 2218 Frankford Ave. in Fishtown.

The space, formerly home to Tierce and the Pickled Heron, is across the street from the seasonal Tired Hands Biergarten, which initially opened for several months in late September at 2213 Frankford Ave. as the High Harvest Biergarten. It’s also about a block away from the forthcoming Aether, a seafood restaurant from Mistral’s Fia Berisha and Elements’ Stephen Distler.

“It’s a symbiotic thing,” Tired Hands co-founder Julie Foster said. “Beer will be available at the restaurant, and the beer garden is a lovely outdoor opportunity for folks coming through.”

St. Oner’s, Tired Hands wrote online, will feature space for 50 diners, as well as a six-seat bar. On tap will be “about a dozen beers” from Tired Hands’ Fermentaria, Brew Cafe, and Dispensary, as well as the company’s 333 Kombucha and natural wines. Tired Hands’ Awake Minds espresso, which co-founder Jean Broillet Broillet IV said the company will roast itself thanks to a facility in the works in Broomall, also will be available.

Food service will focus on “stony bologna Chinese inspired/classic American” dishes and will feature a special bar menu for patrons able to grab one of its limited seats. There, Broillet said, the idea is to present items like “mapo tofu hot dogs,” among other “far out” offerings.

Food will be available to not only patrons of St. Oner’s, but also the nearby Biergarten. As some fans noted last year, the Biergarten lacked food service, offering only small snacks like beef jerky while allowing guests to bring in food from surrounding restaurants. With that in mind, Broillet called opening St. Oner’s an “intuitive choice.”

“We try to control the entire experience,” he said. “So, with a beer garden without food, it didn’t make much sense.”

Although beer will not be brewed on site, Tired Hands fans will be able to buy four-packs of beer, like the company’s popular Alien Church and HopHands, for carryout at St. Oner’s.

St. Oner’s is the company’s latest foray into establishing a foothold in Philadelphia. It has expanded similarly in Ardmore, where it operates three retail locations, as well as a barrel-aging program.

Founded in 2011, Tired Hands is among the most visible breweries in the Philadelphia area, thanks to its popularization of now-common hazy and milk shake IPA beer styles. The brewery attracts droves to its Ardmore Fermentaria for weekly beer releases, when a line of people often wraps around the block. Though most of the brewery’s business is direct to drinkers, its beers are also available on tap around the region.

When St. Oner’s will open remains up in the air, as are hours of operation. Broillet and Foster declined to comment about a potential opening date.