Donovan Mitchell scores 35 as Cavs blow out the Sixers, 133-107

Donovan Mitchell had 35 points and nine assists, Darius Garland scored 20 points before leaving with an injured foot and the Cleveland Cavaliers beat the 76ers 133-107 on Wednesday night.

Garland was ruled out for the game late in the third quarter when he hurt his right foot diving for a loose ball. Garland already had surgery in June on the injured left big toe that hampered him during Cleveland’s exit from the playoffs last season.

The All-Star guard averaged 17.9 points after a slow start this season as he recovered from surgery. Garland continued his recent hot streak and shot 8-for-13 against the Sixers.

» READ MORE: Sixers’ Dominick Barlow leaves Cavaliers game with back contusion

Joel Embiid scored 20 points and hit a three-pointer that helped him reach 13,000 career points, the seventh player in team history to hit that mark.

Paul George had 17 points for the Sixers in the opener of a two-game series.

Sixers fans booed the team off the court in the third quarter headed into a timeout and trailing 75-53.

Tyrese Maxey and Quintin Grimes hit a pair of threes during a 10-0 run and Embiid — who just earlier landed his 7-foot-2 frame on two rows of unsuspecting fans when he dove for a loose ball — buried a three of his own that made it 79-66.

The good times were short-lived, and fans headed for the exits as the Cavs stretched the lead to 22 midway through the fourth.

Sixers forward Dominick Barlow needed help up from the court and into the locker room after his legs gave out on him and he landed hard on his back and head on a driving layup attempt. He suffered a back contusion.

» READ MORE: Sixers appreciate two-game sets, a scheduling quirk that offers ‘small preview’ of playoffs

De’Andre Hunter hit early threes that stretched Cleveland’s lead to 30-14 and 60-47 headed into halftime. Hunter and Evan Mobley both scored 17 points. Mobley grabbed 13 rebounds.

The teams play again Friday at Xfinity Mobile Arena (7 p.m., ESPN).