Eagles open as underdogs against the Jaguars in London; Super Bowl odds plummet after latest loss
The Birds have lost two straight, and the Jags have won two straight. Will things change when the two sides face off overseas?

The Eagles blew a late lead as they fell to the Los Angeles Rams, 24-20, Sunday for their second consecutive loss. Now, the 2-2 Birds will prepare to travel to London to take on their Week 5 opponent, the Jacksonville Jaguars.
From the Eagles’ chances this weekend to updates on their Super Bowl odds, here’s what the oddsmakers are saying at two of the biggest sportsbooks …
Eagles-Jaguars odds
Despite a 10-point lead heading into halftime, the Eagles were held scoreless in the second half, and allowed the Rams to score 14 unanswered points on the way to their second loss of the season. They also have a ton of unanswered injury questions, including Saquon Barkley and Quinyon Mitchell, both of whom left Sunday’s loss and didn’t return.
Meanwhile, the Jaguars (3-1) are coming off two straight wins — a 35-6 rout of the New England Patriots, followed by a 22-17 victory over the Cincinnati Bengals — and have the best point differential (plus-51) in the AFC.
» READ MORE: ‘It’s over’: Eagles' O-line is ‘hot garbage,’ Nick Sirianni is to blame for Rams loss, and what else they’re saying
Now, the two teams will travel to London for their Week 5 matchup. They last played each other in November 2024, when the Eagles defeated the Jaguars at home in a game that is remembered more for one specific play (Saquon Barkley’s iconic backward hurdle) than the actual result (a 28-23 Eagles’ win).
As they prepare to meet again Sunday, the Eagles enter the neutral-site matchup as 5.5-point underdogs at both FanDuel and DraftKings, marking the second straight week in which they’re underdogs, something that hasn’t happened since 2023.
Spread: Eagles +5.5 (-105); Jaguars -5.5 (-115)
Moneyline: Eagles (+205); Jaguars (-250)
Total: Over 42.5 (-115); Under 42.5 (-105)
Spread: Eagles +5.5 (-108); Jaguars -5.5 (-112)
Moneyline: Eagles (+195); Jaguars (-238)
Total: Over 42.5 (-118); Under 42.5 (-102)
NFC odds update
At DraftKings, the Eagles’ odds of winning the NFC have fallen again following the team’s loss to the Rams. They now trail the Detroit Lions and Minnesota Vikings with the seventh-best odds.
Super Bowl odds
The Eagles’ Super Bowl odds have also fallen at both sportsbooks after dropping two straight, and they’re now below their Week 5 opponent as well. The Rams and Buffalo Bills still top the list as early Super Bowl favorites.
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