Where to stay
Rosewood Hotel 10 Norte #1402, Col. Barrio del Alto 011-52-222-122-2300 rosewoodhotels.com/en/puebla The fourth Rosewood in Mexico, this newly opened 78-room property incorporates stunning Colonial architecture and work by Mexican artisans. There's also a rooftop pool, offering scenic views of Mexico's twin volcanoes. Rooms from $225.
Where to eat
Mural de los Poblanos Avenida 16 de Septiembre 506, Centro Historico 011-52-222-242-0503 or 011-52-222-242-6696 elmuraldelospoblanos.com This classic restaurant is named for the detailed mural on one of the dining room walls, depicting characters from Puebla society past and present. On the menu, don't miss the mole sampler, which comes with chicken, turkey, pork, or shredded duck and five kinds of mole sauce ($12.65). Breakfast daily from 8 a.m. to noon; lunch and dinner from 1 p.m. until about 11 p.m.
What to do
International Museum of the Baroque Via Atlixcayotl 2501, Puebla 011-52-222-326-7130 or 011-52-222-326-7131 mib.puebla.gob.mx/en Designed by Pritzker Architecture Prize-winning Japanese architect Toyo Ito, Open 10 a.m. to 7 p.m. Tuesday through Sunday. Admission is about $4.20; Sundays free.